Lecture: Theoretische Biophysik (Teil 1) - Details
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General information

Course name Lecture: Theoretische Biophysik (Teil 1)
Course number PHM-0085
Semester WS 2020/21
Current number of participants 0
expected number of participants 10
Home institute Institut für Physik
Courses type Lecture in category Teaching
First date Monday, 02.11.2020 10:00 - 11:30
Participants Studierende Master Physik und Mathematik
Pre-requisites Gute Kenntnisse der Statistischen Physik
Learning organisation Dauer: 2 Semester (jeweils 2 SWS Vorlesung, 1 SWS Übung )

Die Vorlesung findet über "zoom" statt.
Performance record Bestehen der Modulprüfung
Online/Digitale Veranstaltung Veranstaltung wird online/digital abgehalten.
Hauptunterrichtssprache englisch
Weitere Unterrichtssprache(n) deutsch
Literaturhinweise • P. Nelson, Biological Physics: Energy, Information, Life (Freeman, New York, 2004)
• M. B. Jackson, Molecular and Cellular Biophysics (Cambridge University Press, 2006)
• J. Keener and J. Sneyd, Mathematical Physiology (Springer, New York, 2001)
• T. L. Hill, Free Energy Transduction and Biochemical Cycle Kinetics (Dover Publications, 2004)
• R. Nossal and H. Lecar, Molecular and Cell Biophysics (Addison-Wesley, Redwood City, 1991)
• T. D. Pollard, W. C. Earnshaw, and J. Lippincott-Schwartz, Cell Biology, second edition (Spektrum Verlag,

Rooms and times

No room preference
Monday: 10:00 - 11:30, weekly


Inhalte (Teil 1):
• Cell structure and organization. Molecules of life, structure-function relations. Importance of dynamics, spatial and time scales
• Molecular forces in biological structures. Entropic forces and importance of electrostatics. Energy scales. Molecular dynamics and visualization
• Global transitions in proteins. Two-state thermodynamical model , Arrhenius kinetics, and beyond
• Biochemical reactions: macroscopic enzyme kinetics and stochastic effects in real cells
• Gene-protein circuits (genetic regulation), genetic switches and oscillators